Vitamin K2

Menaquinone-7 — the K vitamin that partners vitamin D

All articles checked for accuracy against the GB NHC Register and all sources have citations with verified links to their relevant studies.

Vitamin K2 (menaquinone-7) is the K-family vitamin often paired with vitamin D3. WellsparQ uses MK-7 in small, specified amounts and flags one important interaction to be aware of.

This article explains what vitamin K2 (MK-7) is, why manufacturers pair it with vitamin D3, where dietary K1 and K2 come from, typical dosing and labelling in the EU, how WellsparQ uses MK-7 in its range, and the single safety interaction that needs attention. It focuses on biology, regulatory context and product placement rather than health promises.

Ingredient Snapshot

What it is

A fat‑soluble vitamin form (menaquinone‑7) used in supplements.

Where from

Menaquinone‑7 (MK‑7), produced by bacterial fermentation; found in fermented foods.

Known for

Involved in activating Gla proteins that bind calcium; often paired with vitamin D3 in formulations.

In WellsparQ

• LipoD3K2 Drops100 µg MK-7 (133.3% NRV)
• VitaralDaily36537.5 µg (50% NRV)

For reference

• EU labelling NRV75 µg/day

Vitamin K is best known for its role in blood clotting, but that is only half the story. The vitamin comes in two families — K1 and K2 — and it is K2, in particular the form called menaquinone-7 (MK-7), that has drawn research interest for its role in activating proteins outside the clotting system. WellsparQ uses MK-7 in a small, deliberate way, most notably paired with vitamin D3. It is a nutrient we treat carefully: the sourcing is specific, the doses are honest, and there is one important safety interaction to flag.

What vitamin K is

Vitamin K is a fat-soluble vitamin that exists as K1 (phylloquinone), found in green leafy plants, and K2 (the menaquinones, MK-n), produced by bacteria and found in fermented foods and animal products ^¹. Its established biochemical job is as a cofactor for the enzyme that carries out gamma-carboxylation — a chemical step that switches on a group of "Gla" proteins, so that they can bind calcium ^¹². These include the clotting factors in the liver and, elsewhere in the body, proteins such as osteocalcin (in bone) and matrix Gla protein (in blood-vessel walls) ^¹². This is a description of the vitamin's biology, established in nutrition science — not a benefit attached to any product.

Why MK-7, and why alongside D3

Among the K2 forms, MK-7 has a longer chain and a notably longer half-life in the blood than either K1 or the shorter MK-4, which is why it is a common choice in supplements aiming for a steady, once-daily presence ^²³. Vitamin K2 is frequently formulated together with vitamin D3, as in WellsparQ's LipoD3K2 Drops: the pairing reflects the fact that both vitamins are involved in how the body handles calcium, and both are fat-soluble and absorbed similarly ^³. This is presented as formulation rationale and background biology, not as a health promise.

How much, and from where

The Nutrient Reference Value used on European labels is 75 µg ^⁴. Dietary K1 comes mainly from kale, spinach, broccoli and other greens; K2 (menaquinones) comes from fermented foods — natto is exceptionally rich — and, in mixed diets, from some animal products ^¹⁵.

Where vitamin K2 appears in the WellsparQ range

Vitamin K2 is a small, targeted entry in just two formulas.

Source: WellsparQ Supplements Database. The MK-7 used is produced by fermentation; suitability (including vegan status) is confirmed per product in our database.

A safety interaction that must be flagged

Vitamin K has one genuinely important caution: it interacts with vitamin K antagonist anticoagulants such as warfarin, whose entire mode of action is to block vitamin K recycling ^¹. A change in vitamin K intake — up or down — can alter how well these medicines work. Anyone taking warfarin or a similar anticoagulant should not start a vitamin K supplement without speaking to their doctor or pharmacist first ^¹. More generally, anyone pregnant, breastfeeding or on regular medication should check before use. For everyone else, vitamin K has a good safety record and no Tolerable Upper Intake Level has been set ^¹.

Where it fits your day

Vitamin K2 is a specialised, quietly used nutrient in the WellsparQ range — chosen in its long-acting MK-7 form and placed where it makes formulation sense, chiefly alongside vitamin D3. It is measured to the microgram, sourced deliberately, and accompanied by the one safety note that genuinely matters. A small addition, honestly handled.

Rooted in nature. Backed by research.